Fall Research Expo 2021

Adaptive Optics Imaging for the Study of Retinal Photoreceptors

Adaptive optics scanning laser ophthalmoscopy (AOSLO) enables visualization of retinal structure with subcellular resolution. Consisting of a wavefront sensor and deformable mirror, AO systems correct the optical aberrations of the eye. Combined with imaging technology, including a light source, optical scanners, and detectors, AOSLO imaging grants us the ability to study properties of individual photoreceptors, such as size and density, in the living eye (Burns et al., 2019). My project will focus on the visualization of AO images in the form of retinal “montages” and compare how the structure of the retina varies between healthy and diseased patients.

PRESENTED BY
PURM - Penn Undergraduate Research Mentoring Program
College of Arts & Sciences 2024
Advised By
Jessica Morgan
Assistant Professor of Ophthalmology
Join Allyson for a virtual discussion
PRESENTED BY
PURM - Penn Undergraduate Research Mentoring Program
College of Arts & Sciences 2024
Advised By
Jessica Morgan
Assistant Professor of Ophthalmology

Comments

Well done, Allyson!  What a fascinating project.  I’m curious about how common Choroideremia is and whether the findings you’ve got here can be adapted/expanded to other degenerative eye diseases?  Do you think you’ll be able to apply your methods to additional patients, or is 3 sufficient to be confident in your results?