The main goal of this project was to define a co-chaperone network of MyBPC and determine its other client proteins. We wanted to determine the other clients that the HSP 70 chaperone family interacts with, ultimately allowing us to find a way to modulate co-chaperones specific to MYBPC that won’t interfere with the other clients that HSP 70 interacts with. This was achieved using siRNA to knockdown specific proteins.